Selective reduction, also called multi-fetal pregnancy reduction, is a medical procedure used to reduce the number of fetuses in multiple pregnancies such as triplets or quadruplets. It helps improve maternal safety and increases the chance of a healthy pregnancy.

Central nervous system (CNS) malformations are among the most common congenital abnormalities. Neural tube defects are the most frequent, occurring in approximately 1–2 cases per 1000 births, and require early detection for effective management.

An intrauterine transfusion delivers blood to an Rh-positive fetus whose red blood cells are destroyed by Rh antibodies. This procedure replaces damaged fetal cells, protecting the baby from anemia and other complications caused by maternal sensitization.