For many women, lifestyle changes can help relieve PMS symptoms. But depending on the severity of your symptoms, your doctor may prescribe one or more medications for premenstrual syndrome.

The success of medications in relieving symptoms varies among women. Commonly prescribed medications for premenstrual syndrome include:

1. Antidepressants:
   Selective serotonin reuptake inhibitors (SSRIs) have been successful in reducing mood symptoms. These medications are generally taken daily. But for some women, the use of antidepressants may be limited to the two weeks before menstruation begins.
   
   

2. Nonsteroidal anti-inflammatory drugs (NSAIDs):
   NSAIDs when taken before or at the onset of your period can ease cramping and breast discomfort.
   
   

3. Diuretics:
   When exercise and limiting salt intake aren’t enough to reduce weight gain, swelling, and bloating, taking water pills can help your body shed excess fluid through your kidneys. Diuretics can help ease some of the symptoms of PMS.
   
   

4. Hormonal contraceptives:
   These prescription medications stop ovulation, which may bring relief from symptoms.